Cancer metastasis

1, the transfer of cancer Why? The transfer of cancer cells may be due to a physical wake-up sleeping in embryonic development-related transcription factor-induced. In general, to carry out the transfer of cancer cells will be divided into several stages: the first phase of the violations referred to as, at this stage in the cancer cell will release the connection between cancer cells, cancer cells make "free" and can be moved to In other places. The second stage is called in dialysis, cancer cells through the blood vessels or lymphatic endothelial into the circulatory system. The third phase known as extravasation, at this stage, the circulatory system after a tour of the baptism of survivors will pass through the microvascular endothelial cells to reach the others. The final stage of the cancer cells is that these immigrants to the New World, among other organizations in the formation of strong proliferation of malignant tumor metastasis. Although there are some disclosure of research and transfer of related genes, but most of the research are cancer cells will be injected into the circulatory system, so they lack the time and with violations of the role of dialysis-related genetic research. Massachusetts Institute of Technology's Whitehead Institute, led by Robert Weinberg's research team, recently published with the early transfer of cancer-related research. First of all, they use the popular microarray analysis will be transferred to the mouse breast cancer cell gene expression, they can find a transcription factor: Twist. The transcription factor in embryonic development of some of the process, the shoulders, as well as lead to cell mobile reorganization. And similar organizations, as well as mobile cell remodeling in the case of tumor metastasis will occur when. They found that Twist will make E-cadherin from the control of the role of cell adhesion failure, and to the creation of the epithelial cell - mesenchymal transformation. Twist and blocked the performance of the cancer cells will reduce the extent of the transfer, and in the circulatory system have reduced the number of cancer cells. In addition to human breast cancer in invasive lobular carcinoma were also observed Twist inhibits E-cadherin. Therefore, Weinberg and others speculated that the reason for the transfer of cancer cells, may be due to wake up the sleeping body for a long time, in charge of early embryonic development of gene patterns in order to start the related procedure, it was terrible the ability to transfer. In the future clinical development of the drug may be able to contain this type of Twist gene expression and to avoid tumor metastasis; or can these genetic screening, early detection of tumors to the future and provide necessary medical treatment. Maybe after the cancer is no longer so terrible a scourge, and other chronic diseases will be not necessarily. 2, the way the transfer of cancer Cancer is a very "greedy", it will go it may reach anywhere, and there are 3 main paths: First, lymph node metastasis Lymphatic metastasis of the first general, so for tumor resection, lymph node dissection to be carried out; radiation exposure in addition to primary tumor lesions, but also the surrounding lymph node irradiation. Throughout the whole body of the lymphatic system, the transfer of cancer cells is the ideal choice and access. Lymphatic metastasis often from far and near, such as the first transfer to the homolateral breast cancer axillary lymph nodes, and then transferred to the clavicle, under the lymph nodes, or even the opposite axillary lymph nodes. Direct invasion of vascular or lymphatic vessels into the cancer cells, with the blood flow to reach other parts of the body such as lung, brain, liver and bone, and so on, and this is the transfer of blood. Gastrointestinal cancer often transferred to the liver and lung, breast, kidney, osteosarcoma, and so often transferred to the lung, lung to brain easy, easy to prostate cancer metastasis to the bone. Second, the transfer of blood Chemotherapy is to avoid the transfer of cancer cells through the blood line, and the drug "along the way," the eradication of cancer cells. Third, the transfer of planting There is also a relatively small shift is the transfer of cultivation. If the surface of cancer cells from the tumor off, "out" in the chest and abdominal cavity of spinal cord and brain, etc., will "take root." These generally take place in the lower part of the cavity, such as rib angle diaphragm, bladder rectum Waterloo, etc. base. Ordinary people love to say something carcinogenic, in fact, we do not eat as long as we can not say what will not get cancer, or what would have access to cancer. Have not yet found any of the factors is a necessary factor-induced cancer. Beat cancer is the most important early discovery, early cancer can be cured most. To this end, we must first regular physical examination, and the other is uncomfortable to see some of the symptoms may be related to cancer, do not feel pain until the doctor.